CORE RawRev Grain Free Natural Puppy Dry Dog Food Puppy Recipe with Freeze Dried Turkey 4lb Bag

⚪ Safe synthetic at label levels: pyridoxine HCl is synthetic vitamin B6, and it's the standard, effective form used across pet food. Dogs require B6 for protein metabolism and neurotransmitter production, and deficiency causes anaemia and seizures. The reason for noting it at all is that B6 has an unusually narrow window at the top end for a B vitamin: chronic excess causes peripheral neuropathy — nerve damage in the limbs and loss of coordination. That's a concern for over-supplementation, not for its presence in a balanced food.

Cholecalciferol is vitamin D3 — the standard, AAFCO-required form of vitamin D in complete dog food, and its presence on a label is expected rather than alarming. Dogs cannot make meaningful vitamin D in their skin from sunlight the way people do, so it has to come from the diet. Two things are worth knowing. D3 is more potent than D2 (ergocalciferol) and has a narrower safety margin — it is the form used in rodenticides. And the real-world risk is manufacturing error, not the ingredient: FDA recalls in 2018–19 found dog foods containing up to 70x the intended vitamin D, causing hypercalcemia, kidney failure and deaths across brands including Hill's, Nutrisca, Sunshine Mills, Kroger and ELM. An ingredient label cannot tell you the amount, only that it is present — so this is flagged for awareness, not as a mark against the food.